The Ley lab studies atherosclerosis, the pathomechanism underlying most cardiovascular disease. We focus on the adaptive immune system. We work on the autoimmune aspect of atherosclerosis, mainly on the CD4 and CD8 T cell responses.
Klaus Ley, M.D.
Founding Co-Director, Immunology Center of Georgia (IMMCG)
Georgia Research Alliance Bradley Turner Eminent Scholar in Immunology
Professor, Department of Physiology
Medical College of Georgia at 麻豆官网首页入口
The lab uses human samples from patients with the disease we study: cardiovascular disease including coronary artery disease. Major methods we use:
Immunology Center of Georgia (IMMCG)
Health Sciences Campus
1410 Laney Walker Blvd, CN4205
706-446-0296
Anusha Bellapu
India
Margaret Beddall
Pei Xiong Liew, PhD
Singapore
Mikhail Fomin, MSc
United States of America
Lauren Fogel
Devadatta Ashok Gosavi
Smriti Parashar, PhD
India
Yan Wang, PhD
China
Megh Mehta
United States of America
Aderonke Fakayode
Nigeria
Xuemei Xie
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Wu, Y., Cao, Z., Liu, W., Cahoon, J. G., Wang, K., Wang, P., Hu, L., Chen, Y., Moser, M., Vella, A. T., , Wen, L. & Fan, Z., Dec 2025, In: Cell Communication and Signaling. 23, 1, 12. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Mysona, D. P., Shah, A., Jaeger, N., Almadadi, A., Orr, B., , , , , , & , Oct 2025, In: Cancer Immunology, Immunotherapy. 74, 10, 318. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Vu, H. N., Lee, M., Situ, A. J., An, W., , Kim, C. & Ulmer, T. S., Sep 23 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 38, e2507966122. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Mehta, M., Li, Y., Parashar, S., Ramirez, C., McKay, H., Landay, A., Aherrahrou, R., Advani, A., Patel, R., Kaplan, R., Lazar, J., Anastos, K., Hanna, D. B., Qi, Q. & , Sep 10 2025, In: International journal of molecular sciences. 26, 18 Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Cappenberg, A., Oguama, M., Richter, M., Margraf, A., Amini, W., Lindental, P., Mersmann, S., Bardel, B., Block, H., Vogl, T., Soehnlein, O., , Rossaint, J. & Zarbock, A., Sep 4 2025, In: Blood. 146, 10, p. 1194-1206 13 p. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Mansouri, S., , , , , , Ahlman, M. A., Westney, G. E., Ghali, J. & , Aug 2025, In: HeartRhythm Case Reports. 11, 8, p. 804-807 4 p. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Oliaeimotlagh, M., Kumar, S., Taraskin, A., Armstrong Suthahar, S. S., Suryawanshi, V., & , Jul 21 2025, In: Cell Reports Methods. 5, 7, 101088. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Roy, P., Bellapu, A., Suthahar, S. S. A., Oliaeimotlagh, M., Lyu, Q., Parashar, S., Makings, J., Wu, R., Kumar, S., Mehta, M., , Sette, A., McNamara, C. A. & , Jul 2025, In: Nature Cardiovascular Research. 4, 7, p. 841-856 16 p. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Gosavi, D. & , May 2025, In: Nature Cardiovascular Research. 4, 5, p. 500-502 3 p. Research output: Contribution to journal 鈥 Comment/debate 鈥 peer-review |
Armstrong, S. S., Chen, D. G., Kumar, S., Heath, J. R., Feinstein, M. J., Greenland, J. R., Calabrese, D. R., Lanier, L. L., & Shemesh, A., Feb 2025, In: International journal of molecular sciences. 26, 3, 1369. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Nettersheim, F. S., Brunel, S., Sinkovits, R. S., Armstrong, S. S., Roy, P., Billitti, M., Kobiyama, K., Alimadadi, A., , Lu, L., Zoccheddu, M., Oliaeimotlagh, M., Benedict, C. A., Sette, A. & , Jan 2025, In: Nature Immunology. 26, 1, p. 105-115 11 p., 812769. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Suthahar, S. S. A., Nettersheim, F. S., Alimadadi, A., Wang, E., Billitti, M., Resto-Trujillo, N., Roy, P., , & , Sep 1 2024, In: Cardiovascular Research. 120, 13, p. 1577-1589 13 p. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Khan, A., Roy, P. & , Sep 2024, In: Nature Reviews Immunology. 24, 9, p. 670-679 10 p. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Khan, A. & , Jul 2024, In: Cell Research. 34, 7, p. 467-468 2 p. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Frias-Anaya, E., Gallego-Gutierrez, H., Gongol, B., Weinsheimer, S., Lai, C. C., , Sriram, A., Bui, C. M., Nelsen, B., Hale, P., Pham, A., Shenkar, R., Debiasse, D., Lightle, R., Girard, R., Li, Y., Srinath, A., Daneman, R., Nudleman, E. & Sun, H. & 8 others, , Jun 1 2024, In: Arteriosclerosis, thrombosis, and vascular biology. 44, 6, p. 1246-1264 19 p. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Stroope, C., Nettersheim, F. S., Coon, B., Finney, A. C., Schwartz, M. A., , Rom, O. & Yurdagul, A., Apr 2024, In: Nature Metabolism. 6, 4, p. 617-638 22 p. Research output: Contribution to journal 鈥 Review article 鈥 peer-review |
Chatterjee, N., , Durant, C. P., Wu, R., McSkimming, C., Drago, F., Kumar, S., Valentin-Guillama, G., Miller, Y. I., McNamara, C. A., , Taylor, A., Alimadadi, A. & , Mar 2024, In: International journal of molecular sciences. 25, 5, 2894. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Gazzi, A., Fusco, L., , Keshavan, S., Shin, Y., Grivel, J. C., Rinchai, D., Ahmed, E. I., Elhanani, O., Furesi, G., Rauner, M., Keren, L., , Casiraghi, C., Bedognetti, D., Fadeel, B. & Delogu, L. G., Feb 2024, In: Nano Today. 54, 102084. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Sl眉tter, B. & , 2024, In: Frontiers in immunology. 15, 1440283. Research output: Contribution to journal 鈥 Editorial 鈥 peer-review |
Roy, P., Suthahar, S. S. A., Makings, J. & , 2024, In: Frontiers in immunology. 15, 1302031. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Pattarabanjird, T., Nguyen, A. T., McSkimming, C., Dinh, H. Q., Marshall, M. A., Ghosheh, Y., Gulati, R., Durant, C., Vallejo, J., Saigusa, R., Drago, F., Guy, T. V., Premo, K., Taylor, A. M., Paul, S., Kundu, B., Berr, S., Gonen, A., Tsimikas, S. & Miller, Y. & 4 others, , Dec 2023, In: Nature Cardiovascular Research. 2, 12, p. 1328 1 p. Research output: Contribution to journal 鈥 Comment/debate 鈥 peer-review |
Pattarabanjird, T., Nguyen, A. T., McSkimming, C., Dinh, H. Q., Marshall, M. A., Ghosheh, Y., Gulati, R., Durant, C., Vallejo, J., Saigusa, R., Drago, F., Guy, T. V., Premo, K., Taylor, A. M., Paul, S., Kundu, B., Berr, S., Gonen, A., Tsimikas, S. & Miller, Y. & 4 others, , Nov 2023, In: Nature Cardiovascular Research. 2, 11, p. 1003-1014 12 p. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Freuchet, A., Roy, P., Armstrong, S. S., Oliaeimotlagh, M., Kumar, S., , Ali, A. J., Khan, A., Makings, J., Lyu, Q., Winkels, H., Wang, E., Durant, C., Ghosheh, Y., Gulati, R., Nettersheim, F. & , Oct 2023, In: Nature Immunology. 24, 10, p. 1748-1761 14 p. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Fusco, L., Gazzi, A., Shuck, C. E., , Ahmed, E. I., Giro, L., Zavan, B., Yilmazer, A., , Bedognetti, D., Gogotsi, Y. & Delogu, L. G., Aug 18 2023, In: Small Methods. 7, 8, 2300197. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Kiss, M. G., Papac-Mili膷evi膰, N., Porsch, F., Tsiantoulas, D., Hendrikx, T., Takaoka, M., Dinh, H. Q., Narzt, M. S., G枚derle, L., Ozsv谩r-Kozma, M., Schuster, M., Fortelny, N., Hladik, A., Knapp, S., Gruber, F., Pickering, M. C., Bock, C., Swirski, F. K., & Zernecke, A. & 4 others, , Aug 8 2023, In: Immunity. 56, 8, p. 1809-1824.e10 Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Lyu, Q., Wang, Y. & , Aug 2023, In: Journal of Leukocyte Biology. 114, 2, p. 109-110 2 p. Research output: Contribution to journal 鈥 Editorial 鈥 peer-review |
Zernecke, A., Erhard, F., Weinberger, T., Schulz, C., , Saliba, A. E. & Cochain, C., Jun 1 2023, In: Cardiovascular Research. 119, 8, p. 1676-1689 14 p. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Lin, J., Ehinger, E., Hanna, D. B., Qi, Q., Wang, T., Ghosheh, Y., Mueller, K., Anastos, K., Lazar, J. M., Mack, W. J., Tien, P. C., Berman, J. W., Cohen, M. H., Ofotokun, I., Gange, S., Liu, C., Heath, S. L., Tracy, R. P., Hodis, H. N. & Landay, A. L. & 2 others, , May 2023, In: PloS one. 18, 5 May, e0285926. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Wang, Z., Zhang, X., Lu, S., Zhang, C., Ma, Z., Su, R., Li, Y., Sun, T., Li, Y., Hong, M., Deng, X., Rafiee Monjezi, M., Hristov, M., Steffens, S., Santovito, D., Dornmair, K., , Weber, C., Mohanta, S. K. & Habenicht, A. J. R. & 1 others, , Mar 2023, In: Nature Cardiovascular Research. 2, 3, p. 290-306 17 p. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Li, W., Wen, L., Rathod, B., Gingras, A. C., & Lee, H. S., Mar 1 2023, In: Life Science Alliance. 6, 3 Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Lyu, Q. & , Feb 1 2023, In: Arteriosclerosis, thrombosis, and vascular biology. 43, 2, p. 215-217 3 p. Research output: Contribution to journal 鈥 Editorial 鈥 peer-review |
Nettersheim, F. S., Ghosheh, Y., Winkels, H., Kobiyama, K., Durant, C., Armstrong, S. S., Brunel, S., Roy, P., Dileepan, T., Jenkins, M. K., Zajonc, D. M. & , Jan 5 2023, In: Frontiers in Cardiovascular Medicine. 9, 1076808. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
, Wolf, D., Suryawanshi, V., Winkels, H., Kobiyama, K., Makings, J., Kiosses, W. B. & , Jan 2023, In: Cellular and Molecular Life Sciences. 80, 1, 10. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Slysz, J., Sinha, A., DeBerge, M., Singh, S., Avgousti, H., Lee, I., Glinton, K., Nagasaka, R., Dalal, P., Alexandria, S., Wai, C. M., Tellez, R., Vescovo, M., Sunderraj, A., Wang, X., Schipma, M., Sisk, R., Gulati, R., Vallejo, J. & Saigusa, R. & 8 others, , 2023, In: JCI Insight. 8, 17, e171359. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Iqneibi, S., Saigusa, R., Khan, A., Oliaeimotlagh, M., Armstrong Suthahar, S. S., Kumar, S., Alimadadi, A., Durant, C. P., Ghosheh, Y., McNamara, C. A., & , 2023, In: Frontiers in immunology. 14, 1239148. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Pattarabanjird, T., Srikakulapu, P., Ransegnola, B., Marshall, M. A., Ghosheh, Y., Gulati, R., Durant, C., Drago, F., Taylor, A. M., & McNamara, C. A., 2023, In: Frontiers in immunology. 14, 1296668. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Nettersheim, F. S., Armstrong, S. S., Durant, C., Blanco-Dominguez, R., Roy, P., , Suryawanshi, V. & , Dec 2022, In: Scientific reports. 12, 1, 20817. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Lai, C. C., Nelsen, B., Frias-Anaya, E., Gallego-Gutierrez, H., , Herrera, V., Ortiz, E., Sun, H., Mesarwi, O. A., , Gongol, B. & Lopez-Ramirez, M. A., Nov 11 2022, In: Circulation research. 131, 11, p. 909-925 17 p. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Saigusa, R., Roy, P., Freuchet, A., Gulati, R., Ghosheh, Y., Armstrong Suthahar, S. S., Durant, C. P., Hanna, D. B., Kiosses, W. B., , Wen, L., Wu, R., Kuniholm, M. H., Landay, A. L., Anastos, K., Tien, P. C., Gange, S. J., Kassaye, S., Vallejo, J. & & 5 others, , May 2022, In: Nature Cardiovascular Research. 1, 5, p. 462-475 14 p. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
Pattarabanjird, T., Wilson, J. M., Erickson, L. D., Workman, L. J., Qiao, H., Ghosheh, Y., Gulati, R., Durant, C., Vallejo, J., Saigusa, R., Platts-Mills, T. A. E., Taylor, A. M., & McNamara, C. A., 2021, In: Frontiers in Cardiovascular Medicine. 8, 791028. Research output: Contribution to journal 鈥 Article 鈥 peer-review |
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