麻豆官网首页入口

Education

Ph.D., Immunology and Molecular Pathology
University of Florida

B.S., Microbiology and Cell Science
University of Florida

Research Interests

The research interests of the McIndoe laboratory are in bioinformatics and computational biology.  Dr. McIndoe鈥檚 lab focuses on two broad themes of scientific inquiry.  The first is the management and coordination of NIH funded multicenter consortia as  Data Coordinating Centers.  These projects deal with data integration and management of large scale projects in Mouse Metabolism and Diabetic Complications.  The second focus is in algorithm development for the analysis of high-throughput molecular data to provide biological insight into basic biology and disease processes.

Research Projects

Development of Molecular Networks from High Throughput Data 

This area of my lab works on developing molecular networks from both microarray and proteomics data to assess the global molecular signatures that reflect disease states.  Projects include looking at literature mining approaches as well as microarray data for both mRNA and miRNA.   

Diabetic Complications Consortium 

Overall Goals:  Diabetic complications consortium (DiaComp) will bring together a number of projects representing a diverse set of disciplines and technologies with the goal of improving or creating mouse models of human diabetes complications.

Mouse Metabolic Phenotyping Centers 

Overall Goals:  My laboratory is the Coordinating and Bioinformatics Unit for the MMPC.The mission of the MMPC is to advance medical and biological research by providing the scientific community with standardized, high quality metabolic and physiologic phenotyping services for mouse models of diabetes, diabetic complications, obesity and related disorders.

PANDA The Prospective Assessment of Newborns for Diabetes Autoimmunity

 
Overall Goals: This project is a new born screening program for Type I Diabetes.  Individuals are screened at birth for their risk of developing type 1 diabetes and subsequently monitored semi-annually for molecular markers of the diseases.

TEDDY The Environmental Determinants of Diabetes in the Young 

Overall Goals: This project is a new born screening program for Type I Diabetes.  Individuals are screened at birth for their risk of developing type 1 diabetes and subsequently monitored semi-annually for molecular markers of the diseases.

Genetic control of autoimmune exocrinopathy in NOD mice 

Overall gaols: This project is to investigate the molecular and immunological mechanism underlying exocrinopathies in NOD mice.   

Development of Microarray-based Biomarkers for Type 1 Daibetes 

Overall gaols: This project is to develop a biomarkers for the prediction of type 1 diabetes pathogenesis using microarrays.  

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Publications

Eckenrode SE, Ruan QG, Collins CD, Yang P, McIndoe RA, Muir A, She JX
CBGM, Medical College of Georgia, 1120 15th Street, CA-4124, 麻豆官网首页入口, GA 30912, USA.

Yang MC, Yang JJ, McIndoe RA, She JX
Department of Statistics, University of Florida, Gainesville, Florida 32611, USA. yang@stat.ufl.edu

Yang L, Zhao H, Li SW, Ahrens K, Collins C, Eckenrode S, Ruan QG, McIndoe RA, She JX
Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida 32610, USA. yanglj@pathology.ufl.edu

Kraj P, McIndoe RA
Institute of Molecular Medicine and Genetics, Medical College of Georgia, 麻豆官网首页入口, GA 30912, USA.

Wilson KH, McIndoe RA, Eckenrode S, Morel L, Agarwal A, Croker BP, She JX
Center for Biotechnology and Genomic Medicine, Medical College of Georgia, PV6B108, 麻豆官网首页入口, GA 30912-2400, USA. Karen.wilson@kmf.gu.se

Eckenrode SE, Ruan Q, Yang P, Zheng W, McIndoe RA, She JX
Center for Biotechnology and Genomic Medicine, Medical College of Georgia, 麻豆官网首页入口, Georgia, USA.

Wilson KH, Eckenrode SE, Li QZ, Ruan QG, Yang P, Shi JD, Davoodi-Semiromi A, McIndoe RA, Croker BP, She JX
Center for Biotechnology and Genomic Medicine, Medical College of Georgia, 麻豆官网首页入口, Georgia, USA.

Killedar SY, Eckenrode SE, McIndoe RA, She JX, Nguyen CQ, Peck AB, Cha SR, Cha S
Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL 32610, USA.

Collins CD, Purohit S, Podolsky RH, Zhao HS, Schatz D, Eckenrode SE, Yang P, Hopkins D, Muir A, Hoffman M, McIndoe RA, Rewers M, She JX
Center for Biotechnology and Genomic Medicine, Medical College of Georgia, 1120 15th Street, CA4124, 麻豆官网首页入口, GA 30912-2400, United States.

McIndoe RA, Lanzen A, Hurtz K
Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville 32610, USA. rmcindoe@mail.mcg.edu

Hsueh W, Abel ED, Breslow JL, Maeda N, Davis RC, Fisher EA, Dansky H, McClain DA, McIndoe R, Wassef MK, Rabad谩n-Diehl C, Goldberg IJ
Division of Endocrinology, Diabetes, and Hypertension, The David Geffen School of Medicine, University of California, Los Angeles, CA, USA.

Kiviniemi M, Hermann R, Nurmi J, Ziegler AG, Knip M, Simell O, Veijola R, L枚vgren T, Ilonen J, The TEDDY Study Group
Immunogenetics Laboratory and MediCity Research Laboratory, University of Turku, Finland. minna.kiviniemi@utu.fi

The TEDDY Study Group
Various

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Post-Doctoral Fellow

Graduate Students

Current

Research Analyst