Grip Strength
Description
In the grip strength test, the rodent is held by the nape of its neck and the base
of its tail. Its forelimbs are placed on the tension bar and the rat is gently pulled
back until it releases the bar. The distance the rodent pulls the bar before it releases
its paw-grip is measured in grams of resistance by a strain gauge. Hind limb strength
can also be assessed.
Purpose
The purpose of the grip strength test is to evaluate the strength of forelimb and
hind limb muscles. This test is useful in detecting changes in motor function and
muscle strength associated with drugs or other manipulations.
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