706-721-7742
dmattson@augusta.edu
Office: CA-3096 | Lab: CA:3097
706-721-7299
Lab Personnel
Emily Burns
John Henry Dasinger, PhD
Mary Shaw
Sam Walton
EducationAcademic AppointmentsResearch InterestsAwards & HonorsPublications
University of Minnesota-Duluth, Biology, BS, 1984
Medical College of Wisconsin, Physiology, PhD, 1990
Department Chair and Professor, Department of Physiology, Medical College of Georgia, Â鶹¹ÙÍøÊ×Ò³Èë¿Ú
Professor with Tenure, Medical College of Wisconsin
Interim Senior Associate Dean of Research, Medical College of Wisconsin
Associate Professor, Medical College of Wisconsin
Assistant Professor, Medical College of Wisconsin
Studies in the Mattson laboratory examine the normal and pathophysiological regulation of renal function and arterial blood pressure. A particular emphasis is placed on the paracrine, autocrine, and hormonal regulation of renal tubular and vascular function. Additional studies are geared toward an understanding of the genetic basis of hypertension and renal disease. The work performed in my laboratory utilizes techniques taken from molecular biology, biochemistry, immunology, and integrative physiology to address the role of the kidney in the regulation of sodium and water homeostasis and arterial pressure. Studies utilize in vitro measurements of mRNA, protein, enzymatic activity, enzyme kinetics, and cell signaling as well as in vivo measurements of hormone levels, blood flow, blood pressure, and other indices of renal/cardiovascular function in anesthetized and conscious rats and mice. Our experimental models include various strains of inbred and genetically manipulated rats and mice.
Outstanding Dissertation Award, Medical College of Wisconsin
Merck Sharpe & Dohme Travel Fellowship
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Burns-Ray, E. C., Dasinger, J. H., Cherian-Shaw, M., Walton, S. D., Baldwin, K. E., Cormier, A. B., Hasan, S., Fehrenbach, D. J., & , 2025, (Accepted/In press) In: Journal of the American Society of Nephrology. 10.1681/ASN.0000000717. Research output: Contribution to journal › Article › peer-review |
Cowley, A. W., Roman, R. J., , Franchini, K. G., , Makino, A., Taylor, N. E., Evans, L. C., Mori, T., Dickhout, J. G., Jin, C., Miyata, N., Nakanishi, K., Szentiványi, M., Park, F., Skelton, M. M., Kurth, T. & Shimada, S., Dec 1 2024, In: Hypertension. 81, 12, p. 2383-2394 12 p. Research output: Contribution to journal › Review article › peer-review |
Dasinger, J. H., , Walton, S. D., Burns-Ray, E. C., Cherian-Shaw, M., Baldwin, K. E., Fehrenbach, D. J. & , Nov 1 2024, In: Hypertension. 81, 11, p. 2357-2367 11 p. Research output: Contribution to journal › Article › peer-review |
, Dasinger, J. H., Lund, H., Burns-Ray, E. C., Walton, S. D., Baldwin, K. E., Fehrenbach, D. J., Cherian-Shaw, M. & , Jul 1 2024, In: Hypertension. 81, 7, p. 1511-1523 13 p. Research output: Contribution to journal › Article › peer-review |
Walton, S. D., Dasinger, J. H., Burns, E. C., Cherian-Shaw, M., & , Aug 2023, In: American Journal of Physiology - Renal Physiology. 325, 2, p. F214-F223 Research output: Contribution to journal › Article › peer-review |
, Dasinger, J. H. & , Aug 1 2023, In: Kidney360. 4, 8, p. 1181-1187 7 p. Research output: Contribution to journal › Review article › peer-review |
Yang, Y., Liu, H., Liu, Y., Zhou, L., Zheng, X., Yue, R., , Kidambi, S., Liang, M., Liu, P. & Pan, X., Jul 1 2023, In: Briefings in Bioinformatics. 24, 4, bbad241. Research output: Contribution to journal › Article › peer-review |
Spires, D. R., Schibalski, R. S., Domondon, M., Clarke, C., Perez, S., Anwar, F., Burns, E., Saeed, M. I., Walton, S. D., Zamaro, A. S., Amoah, T., Arkhipov, S. N., Christopher, C. J., Campagna, S. R., , Pavlov, T. S. & , Jul 2023, In: American Journal of Physiology - Renal Physiology. 325, 1, p. F105-F120 Research output: Contribution to journal › Article › peer-review |
Lenarczyk, M., Alsheikh, A. J., Cohen, E. P., Schaue, D., Kronenberg, A., Geurts, A., Klawikowski, S., & Baker, J. E., Feb 2023, In: Toxics. 11, 2, 183. Research output: Contribution to journal › Comment/debate › peer-review |
Dasinger, J. H., Walton, S. D., Burns, E. C., Cherian-Shaw, M., & , Dec 2022, In: American Journal of Physiology - Renal Physiology. 323, 6, p. F666-F672 Research output: Contribution to journal › Article › peer-review |
, Dasinger, J. H. & , Nov 1 2022, In: Hypertension. 79, 11, p. 2397-2408 12 p. Research output: Contribution to journal › Review article › peer-review |
, Nov 1 2022, In: Hypertension. 79, 11, p. 2463-2464 2 p. Research output: Contribution to journal › Editorial › peer-review |
Shimada, S., Yang, C., Kumar, V., & Cowley, A. W., Jun 1 2022, In: Hypertension. 79, 6, p. 1180-1189 10 p. Research output: Contribution to journal › Article › peer-review |
Roberts, M. L., Kotchen, T. A., Pan, X., Li, Y., Yang, C., Liu, P., Wang, T., Laud, P. W., Chelius, T. H., Munyura, Y., , Liu, Y., Cowley, A. W., Kidambi, S. & Liang, M., Apr 1 2022, In: Hypertension. 79, 4, p. 761-772 12 p. Research output: Contribution to journal › Article › peer-review |
Fehrenbach, D. J. & , Mar 2022, In: American Journal of Physiology - Renal Physiology. 318, 3, p. F544-F548 Research output: Contribution to journal › Review article › peer-review |
& , Dec 2021, In: Current Hypertension Reports. 23, 12, 45. Research output: Contribution to journal › Review article › peer-review |
Miller, B., Palygin, O., El-Meanawy, A., , Geurts, A. M., Staruschenko, A. & Sorokin, A., Aug 15 2021, In: Life sciences. 279, 119661. Research output: Contribution to journal › Article › peer-review |
, Saravia, F. L., Lund, H., Dasinger, J. H., Fehrenbach, D. J., Alsheikh, A. J., Zemaj, J., Kirby, J. R. & , Aug 2021, In: Acta Physiologica. 232, 4, e13662. Research output: Contribution to journal › Article › peer-review |
Kidambi, S., Pan, X., Yang, C., Liu, P., Roberts, M. L., Li, Y., Wang, T., Laud, P. W., Liu, Y., Rubens, M., Thomas, R., Widlansky, M. E., Beyer, A. M., Liu, Y., Cowley, A. W., Kotchen, T. A., Munyura, Y., Moosreiner, A., & Liang, M., Aug 1 2021, In: Hypertension. 78, 2, p. 434-446 13 p. Research output: Contribution to journal › Article › peer-review |
Dasinger, J. H., , Bukowy, J. D., Lund, H., Alsheikh, A. J., Fehrenbach, D. J., Zemaj, J. & , Jun 2021, In: Pregnancy Hypertension. 24, p. 126-134 9 p. Research output: Contribution to journal › Article › peer-review |
Santillan, M. K., Becker, R. C., Calhoun, D. A., Cowley, A. W., Flynn, J. T., Grobe, J. L., Kotchen, T. A., Lackland, D. T., Leslie, K. K., Liang, M., , Meyers, K. E., Mitsnefes, M. M., Muntner, P. M., Pierce, G. L., Pollock, J. S., Sigmund, C. D., Thomas, S. J., Urbina, E. M. & Kidambi, S., Jun 1 2021, In: Hypertension. 77, 6, p. 1857-1866 10 p. Research output: Contribution to journal › Review article › peer-review |
, May 2021, Physiologist, 64, 3, p. 36-37 2 p. Research output: Contribution to specialist publication › Article |
Basile, D. P., & , Mar 2021, In: Current opinion in nephrology and hypertension. 30, 2, p. 151-158 8 p. Research output: Contribution to journal › Review article › peer-review |
Fehrenbach, D. J., , Dasinger, J. H., Lund, H., Keppel, T., Zemaj, J., Cherian-Shaw, M., Gundry, R. L., Geurts, A. M., Dwinell, M. R. & , Jan 1 2021, In: Hypertension. 77, 1, p. 228-240 13 p. Research output: Contribution to journal › Article › peer-review |
, Dasinger, J. H. & , Jan 1 2021, In: American journal of hypertension. 34, 1, p. 3-14 12 p. Research output: Contribution to journal › Review article › peer-review |
Kidambi, S., Wang, T., Chelius, T., Nunuk, I., Agarwal, P., Laud, P., , Cowley, A. W., Liang, M. & Kotchen, T., Dec 1 2020, In: Scientific reports. 10, 1, 11685. Research output: Contribution to journal › Article › peer-review |
Lenarczyk, M., Laiakis, E. C., , Johnson, B. D., Kronenberg, A., North, P. E., Komorowski, R., Mäder, M. & Baker, J. E., Dec 2020, In: FASEB BioAdvances. 2, 12, p. 705-719 15 p. Research output: Contribution to journal › Article › peer-review |
Shimada, S., , Alsheikh, A. J., Yang, C., Stumpf, M., Kurth, T., & Cowley, A. W., Sep 1 2020, In: Hypertension. 76, 3, p. 849-858 10 p. Research output: Contribution to journal › Article › peer-review |
Dasinger, J. H., & , Jul 2020, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 319, 1, p. R26-R32 Research output: Contribution to journal › Review article › peer-review |
Fehrenbach, D. J., Dasinger, J. H., Lund, H., Zemaj, J. & , May 1 2020, In: Experimental Physiology. 105, 5, p. 864-875 12 p. Research output: Contribution to journal › Article › peer-review |
Alsheikh, A. J., Dasinger, J. H., , Fehrenbach, D. J., Yang, C., Cowley, A. W. & , Apr 2020, In: American Journal of Physiology - Renal Physiology. 318, 4, p. F982-F993 Research output: Contribution to journal › Article › peer-review |
, Alsheikh, A. J., Pan, X., Fehrenbach, D. J., Dasinger, J. H., Lund, H., Roberts, M. L., Kriegel, A. J., Cowley, A. W., Kidambi, S., Kotchen, T. A., Liu, P., Liang, M. & , Oct 1 2019, In: Hypertension. 74, 4, p. 854-863 10 p. Research output: Contribution to journal › Article › peer-review |
Lerman, L. O., Kurtz, T. W., Touyz, R. M., Ellison, D. H., Chade, A. R., Crowley, S. D., , Mullins, J. J., Osborn, J., Eirin, A., Reckelhoff, J. F., Iadecola, C. & Coffman, T. M., Jun 1 2019, In: Hypertension (Dallas, Tex. : 1979). 73, 6, p. e87-e120 Research output: Contribution to journal › Review article › peer-review |
, Lund, H., Fehrenbach, D. J., Dasinger, J. H. & , Jul 2 2018, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 315, 1, p. R28-R35, Research output: Contribution to journal › Article › peer-review |
Miller, B., Palygin, O., Rufanova, V. A., Chong, A., Lazar, J., Jacob, H. J., , Roman, R. J., Williams, J. M., Cowley, A. W., Geurts, A. M., Staruschenko, A., Imig, J. D. & Sorokin, A., Jul 1 2016, In: Journal of Clinical Investigation. 126, 7, p. 2533-2546 14 p. Research output: Contribution to journal › Article › peer-review |
Wade, B., & , Jan 1 2016, In: Current opinion in nephrology and hypertension. 25, 1, p. 22-27 6 p. Research output: Contribution to journal › Review article › peer-review |
De Miguel, C., Rudemiller, N. P., & , 2015, In: Current Hypertension Reports. 17, 1 Research output: Contribution to journal › Review article › peer-review |
Rudemiller, N., Lund, H., Jacob, H. J., Geurts, A. M. & , Mar 2014, In: Hypertension. 63, 3, p. 559-564 6 p. Research output: Contribution to journal › Article › peer-review |
, Lund, H., Guo, C., Rudemiller, N., Geurts, A. M. & Jacob, H., 2013, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 304, 6, p. R407-R414 Research output: Contribution to journal › Article › peer-review |
, Dec 2010, In: American Journal of Physiology - Renal Physiology. 299, 6, p. F1257 Research output: Contribution to journal › Editorial › peer-review |
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Hypertension. 2024 Dec;81(12):2383-2394. doi: 10.1161/HYPERTENSIONAHA.124.21711. Epub 2024 Sep 30. PMID: 39344517
Hypertension. 2024 Nov;81(11):2357-2367. doi: 10.1161/HYPERTENSIONAHA.124.23303. Epub 2024 Sep 20.PMID: 39301728
Hypertension. 2024 Jul;81(7):1511-1523. doi: 10.1161/HYPERTENSIONAHA.123.22608. Epub 2024 May 17.PMID: 38757269