Ali Arbab
Professor
Academic Appointment(s)
Medical College of Georgia
Department of Biochemistry and Molecular Biology
Administration
Department of The Graduate School
Bio
I have 35 years of experience in imaging science, involving MRI, SPECT, CT, ultrasound, and optical imaging modalities. My laboratory is working on targeting the tumor micro-environment of glioblastoma and breast cancers using different engineered exosomes and drug-loaded nano-capsules. We are also working with stroke models to improve recovery using engineered exosomes.
Education
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Ph.D., Medical Scientist.
Yamanashi Medical University, 1998
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MD, Medicine
University of Dhaka, 1988
Awards & Honors
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Grant Reviewer
The National Institutes of Health, 2020
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Grant reviewer
California Institute of Regenerative Medicine, 2017
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Travel Award
Radiological Society of North America (RSNA), 2008
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Fellows Award for Research Excellence (FARE)
The National Institutes of Health, 2003
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Asia-Oceania Young Investigator鈥檚 Award
Japanese Society of Nuclear Medicine, 1999
Courses Taught Most Recent Academic Year
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BIOM 8230
Biology of Proteins in Disease
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BCMB 8201
Cur Topics & Tech in MB
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BCMB 9010
Seminar in BMB
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CURS 2990
Undergrad Research I
Teaching Interests
Tumor neovascularization, Biomedical Imaging,Tumor micro-environment and possible effect after chemotherapy, engineered exosomes in pathophysiology
Scholarship
Selected Recent Publications
- Single episode of moderate to severe traumatic brain injury leads to chronic neurological deficits and Alzheimer鈥檚-like pathological dementia, 2024
Journal Article, Academic Journal
- Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke, 2024
Journal Article, Academic Journal
- Isolation and immunosuppressive functions of myeloid-derived suppressor cell-derived exosomes, 2024
Journal Article, Academic Journal
- Experimental study of processing of PCL (polycaprolactone)-peptides nanoparticles and its biodistribution analysis for drug delivery system, 2024
Journal Article, Academic Journal
- Altering biomolecular condensates as a potential mechanism that mediates cannabidiol effect on glioblastoma, 2024
Journal Article, Academic Journal
Research Interests
> Generation of engineered exosomes to initiate ADCC of targeted cells by NK cells.
> Generation of engineered exosomes to target dying neurons in stroke
> Ultrasound-mediated delivery of exosomes to the stroke area to enhance the better outcome
> Understanding the mechanisms of resistance to antiangiogenic treatment in solid tumors.
> Targeting arachidonic acid metabolites for the treatment of solid tumors.
>Tumor cell-secreted exosomes in modulating tumor micro-environment and niche for distal metastasis.
> Generation of tissue-specific MRI and SPECT contrast agents and drug delivery systems (nano-particles).
> Understand the mechanisms of GVHD to delay it by targeting myeloid cells.
Department Service
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Small animal core advisory committee
2020 - 2025
Role: Committee Member
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Director 3T human MRI core
2023 - 2025
Role: Other
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GCC proteomics core
2021 - 2023
Role: Committee Member
University Service
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PT committee of DCG
2023 - Present
Role: Committee Member
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ARAC
2021 - Present
Role: Committee Member
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Mock Study Section
2019 - 2020
Role: Administrative Assignment, Other
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Steering Committee
2019 - 2020
Role: Committee Member
Professional Service
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NIH study panel
2016 - Present
Role: Reviewer, Grant Proposal
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CIRM
2004 - Present
Role: Member
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Scientific Journals
- 2020
Role: Reviewer
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Various scientific journals
- 2020
Role: Editorial Review Board Member
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